Biomarkers in obese asthma: Age of asthma onset matters!
نویسندگان
چکیده
منابع مشابه
Asthma biomarkers in the age of biologics
The heterogeneous nature of asthma has been understood for decades, but the precise categorization of asthma has taken on new clinical importance in the era of specific biologic therapy. The simple categories of allergic and non-allergic asthma have given way to more precise phenotypes that hint at underlying biologic mechanisms of variable airflow limitation and airways inflammation. Understan...
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Some studies indicate that children born to younger mothers are at a higher risk of wheezing and asthma. To investigate the maternal age associated with asthma in children, a case-control study on 310 asthmatic and 310 non-asthmatic children aged 3 to 4 years was organized during a one-year period. A questionnaire was used to obtain information about the child’s personal susceptibility factor...
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Prevention strategies that delay the onset of asthma may improve clinical outcomes. To identify early life environmental exposures associated with asthma age-of-onset and potential genetic modifiers of these exposures, we studied 1085 subjects with physician-diagnosed asthma and disease onset at or after age two. Subjects reported retrospectively on their exposure to 17 environmental factors be...
متن کاملObesity and asthma: an association modified by age of asthma onset.
BACKGROUND Studies of asthma phenotypes have identified obesity as a component of a group characterized by a high proportion of subjects with adult-onset asthma. However, whether age of asthma onset modifies the association between obesity and asthma is unknown. OBJECTIVES We sought to compare the associations between body mass index (BMI) categories with physiological, inflammatory, and clin...
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Seventy-one cases of bronchial asthma were classified into three types: bronchospasm, bronchospasm-hypersecretion and bronchiolar obstruction types. The characteristics of each type were studied in relation to patient age and age at onset of the disease. In the 71 subjects studied, the most frequent type was the bronchospasm type followed by the bronchospasm-hypersecretion type and bronchiolar ...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2018
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2017.12.989